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Immunomics Analysis Pipeline

Gain Deeper Understanding Of Your Immune System

  • TCR and BCR profiling - full V(D)J recombination analysis across T cell and B cell receptor repertoires
  • Clonotype diversity mapping - identify dominant clones, rare variants and clonal expansion events
  • Functional immune insights - link receptor sequences to antigen specificity, disease state and treatment response
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Complete Immune View. No Manual Work

  • TCR and BCR V(D)J recombination
  • Clonotype assembly and diversity profiling
  • Clonal expansion and convergence
  • HLA typing and immune gene variant calling
  • Repertoire comparison across samples

Globally Trusted By Clinicians And Researchers

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  • Pre-Processing
  • Repertoire Analysis
  • Reports
  • Deliverables

Clean Sample. Accurate Results.

Raw immune sequencing data is processed through rigorous QC, adapter trimming and UMI-based deduplication. Every read is validated before V(D)J assignment begins because one bad read can corrupt an entire clonotype call.

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Every Clone. Counted.

Clonotypes assembled from V(D)J assignments. Diversity indices calculated. Clonal expansion events flagged. CDR3 sequences extracted and linked to antigen specificity databases giving you the full functional landscape of your immune repertoire.

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See Your Data. Get The Story.

Clonotype tables, diversity plots, V gene usage charts and CDR3 length distributions all delivered as interactive HTML reports to your dashboard the moment the run finishes.

See Sample Report
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Ready To Publish

From raw sequencing reads to fully annotated immune repertoire reports every deliverable you need to publish, present or hand off is in your dashboard the moment the pipeline completes.

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Our Pipeline Modules

Three Analyses. One Run.

TCR Profiling

Full TCRα and TCRβ V(D)J analysis. Clonotype assembly, diversity metrics and expansion events automated end to end.

BCR Profiling

IGH, IGK and IGL chain analysis with somatic hypermutation detection and isotype distribution profiling.

HLA Typing

High-resolution HLA typing from NGS data. Immune gene variants called for disease and transplant research.

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Everything Analyzed. Nothing To Code.

Upload your sequencing files and get back TCR profiles, BCR repertoires and HLA types all visualized, annotated and ready to share before your next meeting.

What is immune repertoire sequencing?

Immune repertoire sequencing reads every unique T cell and B cell receptor in your sample mapping the full diversity of your immune response from a single NGS run. No culturing. No guessing. Just a complete picture of every clone your immune system has generated.

How long does an immunomics analysis take?

Most runs complete within hours of submission. A standard TCR or BCR profiling run is typically done the same day. Your dashboard updates live so you always know where things stand no waiting around for a pipeline to silently finish.

What file format do I need to upload?

Raw FASTQ files exactly what your sequencing facility delivers. Paired-end and single-end reads are both supported. Upload once and the pipeline handles QC, alignment, clonotype assembly and reporting automatically.

What does the immunomics report actually include?

You get a clonotype frequency table with full V(D)J assignments and CDR3 sequences, a diversity and clonality dashboard with Shannon entropy and rarefaction curves, V gene usage charts and if HLA typing is included high-resolution allele calls with population frequency annotations. All delivered as shareable interactive HTML to your dashboard.

Can GenomeBeans detect clonal expansion and dominant clones?

Yes and this is one of the most clinically valuable outputs. The pipeline automatically flags expanded and hyperexpanded clones so you can immediately see which T or B cell populations are responding to a pathogen, tumour or vaccine. No manual filtering required.

Is my sequencing data safe and private?

100% private. You own everything you upload. Never shared. Never sold. Results archived for 90 days then permanently deleted. No exceptions. No fine print.

Your Immune System Deserves Better.